A recent systematic review of the association between genetic predisposition and biological complications of dental implants suggested that there is no strong association among specific genetic polymorphisms (IL-1A, IL-1B, IL-17RC) and peri-implantitis, although there was a notable tendency indicating a link between the IL-1 genotype and peri-implantitis [19], [20]. The gene discussed is IL1B; the disease is Peri-Implantitis.