VASH2 and breast cancer: Table I shows the association between VASH2 staining and the clinicopathological characteristics of breast cancer. VASH2 expression was high in 70/99 (70.7%) breast cancer tissues. VASH2 staining was generally higher in grade 3 tissues and those with Ki67 ≥14% (Pearson χ2, P<0.001). These findings indicate that VASH2 may promote proliferation in human breast cancer cells. Fig. 1 displays the representative images of high and low VASH2 expression levels in human breast cancer tissues.