To test if increased GLO1 activity can retard the development of diabetic atherosclerosis, 10‐week‐old GLO1TGApoe−/− male mice and non‐TG Apoe−/− male litter mates maintained on a chow diet were injected with STZ or vehicle and, 6 weeks later, the animals were sacrificed and aortic atherosclerosis was quantified. The gene discussed is GLO1; the disease is aortic atherosclerosis.