APOE and atherosclerosis: To further explore if increased reactive dicarbonyl levels alone can exacerbate atherosclerosis in Apoe−/− mice, we have bred Glo1KD mice that have a 45–65% reduction in GLO1 activity (El‐Osta et al. 2008) onto an Apoe−/− background (Glo1KDApoe−/−mice).