Although Mo-DCs infected with RSV or hMPV have not been found to skew T cells away from the Th1 compartment [39], phenotypic and functional differences between BDCA-1+ and BDCA-3+ mDCs suggest that each subset plays a distinct role in coordination of immune responses during infection, and studies in both mice [40]–[42] and humans [43]–[45] demonstrate a specific role for BDCA-3+ mDCs in the development of Th2 and Treg responses. The gene discussed is THBD; the disease is infection.