Of note, in the here examined cohort, it has recently been shown that mutation in KRAS codon 13, but not in codon 12, was associated with a significantly reduced cancer specific survival which is in line with other previous publications [16], [38], [39], [40], and most previous studies have not considered the prognostic value of specific mutations [7]–[9], [37], [41]. This evidence concerns the gene KRAS and cancer.