High waist- and hip measures were associated with an increased risk of KRAS wild type tumours (ptrend = 0.045 and ptrend = 0.043), KRAS-mutated tumours (ptrend = 0.007 and ptrend = <0.001), as well as BRAF wild type tumours (ptrend = <0.001 and ptrend = <0.001). The gene discussed is BRAF; the disease is neoplasm.