CD40LG and disease arising from reactivation of latent virus: Patients in the uninfected and latent infection groups had roughly equal quantities of IgG and IgM to the M. tuberculosis surface, whole cell lysate, lipoarabinomannan, and cell wall (mean IgG/IgM ratios, −0.24 to 0.32 log10; Figure 1 E and F, , Figure 2 G–H), and modest IgG predominance against secreted proteins (mean IgG/IgM ratios, 0.53 and 0.72 log10; Figure 1 I).