IFNG and infection: In human genital infections, local cervical T-cell infiltrates and genital IFNγ concentrations are significantly elevated during active infection, higher in women with recurrent vs. primary infection, and decreased upon resolution of infection (Figure 1), and (Arno et al., 1990; Loomis and Starnbach, 2002; Agrawal et al., 2007; Ficarra et al., 2008; Sperling et al., 2013).