HDAC9 and Friedreich ataxia: Furthermore, other HDAC inhibitors such as sirtinol (Ota et al., 2006), splitomicin (Biacsi et al., 2008), LBH589 (Garbes et al., 2009), and oxamflatin (Kim et al., 1999) have shown positive effects in other diseases including cancer and/or neurodegenerative disorders and these compounds may also be considered for future FRDA therapy.