Association of multiple variants in the intergenic region and within NLRP1 have been reported to be associated with innate immunity/inflammasome disorders, including vitiligo (Jin et al., 2007), Addison's disease (Zurawek et al., 2010), systemic sclerosis -related pulmonary fibrosis (Dieudé et al., 2011), and type 1 diabetes (Magitta et al., 2009). This evidence concerns the gene NLRP1 and vitiligo.