To examine T-cell response to infectious agent antigens, Maecker et al. characterized the in vitro CD8+ T-cell response in HLA-A*0201+ MM patients and healthy individuals to influenza A and Epstein–Barr virus-derived immunodominant epitopes using major histocompatibility complex (MHC)/peptide tetramers (116). This evidence concerns the gene CD8A and Miyoshi myopathy.