In addition to the GSTP1 SNPs' association with hypertension, our results also show a significant adverse effect of air pollution exposure on AMI for the subjects with AA-genotype in GSTCD SNP rs10516526, OR 2.25 (95% CI 1.25–4.06) per 10 μg/m3 of NO2, and a near null effect estimate for subjects with GA or GG genotypes combined (OR 1.01, 95% CI 0.28–3.73). Here, GSTP1 is linked to hypertensive disorder.