When we treated gastric cancer xenografted nude mice with a HIF-1α-specific inhibitor, echinomycin, for 10 days, echinomycin decreased the expression of miR-382 by 0.2-fold in tumor tissues, confirmed by real-time PCR, indicating that HIF-1α is involved in miR-382 expression in tumor tissues. Here, HIF1A is linked to gastric cancer.