AKT1 and gastric cancer: Therefore, taken together with our results and recent findings from other groups, chemotherapeutic efficacy for gastric cancer can be increased by the inhibition of the AKT/mTOR pathway (50), and cancer progression and metastasis through increased angiogenesis through miR-382 (Figures 3 and 6) can be inhibited by PTEN or antagomiR-382 in hypoxic gastric cancer.