CHL1 and chronic myelogenous leukemia, BCR-ABL1 positive: As displayed in Figure 1A, LASP1 is significantly (p < 0.0001) and highly overexpressed in CML cells compared to all normal tissues and cells, respectively, while it is considerably lower expressed in cells derived from acute myeloid leukemia (AML), common acute lymphoblastic leukemia (cALL) or chronic lymphocytic leukemia (CLL).