FOS and cancer: If another TFBS set V$AP1FJ_Q2 is chosen, the well-known c-JUN interacting partner Fos as well as Il6 are captured in the ‘pathways in cancer (KEGG)’ gene set, and Fos exhibits a very strong co-expression pattern with Jun in many of the virus-treated HeLa cell conditions (Additional file 1: Figure S2c).