Using splice variant-specific primers (Fig.S2), we also determined that macroH2A1.1 transcription was greater in the basal compared to the luminal subgroup of BC cell lines, while mRNA expression levels of macroH2A1.2 or total macroH2A1 mRNA did not differ significantly (Fig.1C). The gene discussed is MACROH2A1; the disease is breast cancer.