In CRSwNP [0,91; IQR: 0,52–1,19] and CF-NP [1,12; IQR: 0,94–1,28], the ratio CD4+ to CD8+ was significantly higher (p = 0,042) compared to CRSsNP [0,525, IQR: 0,48–0,68] mucosa, wheremore cytotoxic T cells were expressed. This evidence concerns the gene CD4 and cystic fibrosis.