Asthmatic patients had the highest number of Th2 cells, this observation also being linked to the expression of SE-IgE antibodies, confirming our earlier analysis based on protein data; those data also showed a great variety of cytokine expression in CRSwNP samples, and a highly increased risk of being asthmatic with the expression of IL-5 and SE-IgE [9]. The gene discussed is IGHE; the disease is chronic rhinosinusitis with nasal polyps.