Further rounds after elimination of DRB1*04:05, *13:02 and *04:01 carriers revealed associations between the remaining DRB1 alleles and RA, particularly for DRB1*09:01 (P = 7.32×10−5, Pc = 0.0020), *01:01 (P = 3.75×10−5, Pc = 0.0010), *14:06 (P = 0.0041, Pc = 0.0995), *10:01 (P = 0.0128, Pc = 0.2936), *04:10 (P = 0.0109, Pc = 0.2399), and *11:01 (P = 0.0236, Pc = 0.4948). This evidence concerns the gene HLA-DRB1 and rheumatoid arthritis.