MEN-1 involves a germline mutation at the 11q13 (a tumor suppressor gene) which encodes for a protein menin and is associated with increased risk of parathyroid, endocrine (thyroid, prostate, testicular, breast, and ovarian), pancreas, and pituitary neoplasia (mostly adenomas) (Mayer, 2005; Morin et al., 2005). The gene discussed is MEN1; the disease is adenoma.