IFNG and psoriasis: A strong IFN-γ genomic (Bowcock et al., 2001) and cellular (Austin et al., 1999) signature is present in psoriasis, and intradermal injection of IFN-γ has been shown to induce several molecular and histological features characteristic of psoriatic lesions in both healthy and psoriatic human skin (Johnson-Huang et al., 2012).