DSP and melanoma: On the other hand, in this context, we do not forget to mention the specific occurrences of individual desmosomal molecules in other ensembles such as desmoplakin in the complexus adhaerentes of parts of lymphatic endothelia (Schmelz and Franke 1993; Hämmerling et al. 2006; Moll et al. 2009), plakophilin Pkp-2 in AJs of certain very proliferative stages of mesenchymal cells (e.g., Barth et al. 2009, 2012; Rickelt et al. 2010; Rickelt 2012) and the “free” Dsg-2 glycoproteins dispersed on the surfaces of certain types of melanoma cells (Schmitt et al. 2007; Rickelt et al. 2008).