However, deletion of a critical region on 18q23 that includes the ZNF407 gene and two other zinc finger genes (ZNF516 and ZNF236), among other genes, is correlated with congenital aural atresia (CAA), which manifests a subset of phenotypes recognized by the 18q deletion (18q-) syndrome [23]. This evidence concerns the gene ZNF236 and Abnormality of the ear.