NUCB2 and Hypoglycemia: Moreover, numerous structures, including hypothalamic nuclei and the medullary dorsal vagal complex (DVC) which is composed of 3 parts: the AP, NTS and dorsal motor nucleus of the vagus nerve (DMNV) belong to the brain vagal-regulatory pathway activated during hypoglycemia and contain a large proportion of nesfatin-1-expressing neurons [11].