Even when SCP3 expression was compared with levels of pAKT using Spearman nonparametric correlation test, SCP3 expression was significantly associated with pAKT expression in both CIN (Spearman's rho = 0.322, P<0.001) and cancer specimens (Spearman's rho = 0.197, P = 0.010). Here, SYCP3 is linked to cervical squamous intraepithelial neoplasia.