Dicer is down-regulated in many tumors, such as transitional cell carcinoma of the urinary bladder (94), neuroblastoma (86), nasopharyngeal carcinoma (88), endometrial cancer (87), breast cancer (102), lung cancer (101, 111), gastric cancer (GC) (112), ovarian cancer (113), and gallbladder adenocarcinoma (90). The gene discussed is DICER1; the disease is ovarian cancer.