NFKB1 and neoplasm: Our group and others have shown that macrophages are abundant in peritoneal ascites fluid and that ovarian tumors have the ability to polarize macrophages to display tumor-promoting characteristics in a nuclear factor-kappaB (NF-κB)-dependent manner (84, 90), but can be “re-educated” toward an anti-tumor phenotype (84) and thus are a potential target for therapy.