INS and neoplasm: The American Food and Drug Agency (FDA) concluded that the evidence presented was inconclusive due to the limitations in how these studies were designed, carried out, and in the data available for analysis [Early Communication about Safety of Lantus (insulin glargine); http://www.fda.gov/Drugs/DrugSafety/PostmarketDrugSafetyInformationforPatientsandProviders/DrugSafetyInformationforHeathcareProfessionals/ucm169722.htm did raise concerns as to whether or not insulin analogs promote cell proliferation and growth of (subclinical) neoplasms.