SLC11A2 and nutritional disorder: Consistent with this are studies showing that iron deficiency is associated with increased Mn content in the brain of rats (Chua and Morgan, 1996; Erikson et al., 2002), in the olfactory epithelium of the DMT1-deficient Belgrade rat (Thompson et al., 2007) and in serum of humans with anemia or an iron deficient diet (Davis et al., 1992; Rahman et al., 2013).