NPY and autism: Reinforcing the hypothesis of an involvement of faulty GABAergic transmission in autism, mice with 15q11-13 duplication and contactin-associated protein-like 2 (CNTNAP2) KO mice -two mutations present in some autistic patients- present autistic-like behaviors associated with increased α5, β3, γ3 subunit mRNAs as well as decreased number of parvalbumin, calretinin and neuropeptid Y interneurons, respectively (Nakatani et al., 2009; Penagarikano et al., 2011).