RD3 and retinal degeneration: Recently, retinal degeneration 3 (RD3), a photoreceptor protein encoded by the gene associated with retinal degeneration in the rd3 mouse, rcd2 collie, and LCA12 patients has been shown to play a crucial role in the trafficking of GC1 and GC2 in photoreceptors (Azadi et al., 2010).