We found significantly increased VEGF serum levels among BCC patients, in comparison with healthy controls (mean 596.7 ± 393.5 pg/ml; range 60.1–931.4 vs. 255.9 ± 174.6 pg/ml; range 42.2–553.0 pg/ml; p < 0.0004). The gene discussed is VEGFA; the disease is skin basal cell carcinoma.