IRF3 and infection: We again observed more productive multiplication for Romero virus in IRF3/7 KO MEF cells (2.5×105 PFU/ml, 5 d.p.i.)than in wt MEF (2.3×104 PFU/ml, 5 d.p.i.), supporting the role of IFN pathway in suppressing JUNV infection in murine cells.