Focus only on multiple hit of interact regions, GRIK3 from chromosome 1 interacts with a region in chromosome 3; SULT4A1 from chromosome 22 interacts with a region on chromosome 12; LRFN2 from chromosome 6 interacts with SORBS1 from chromosome 10; Based on queries from GeneCard database (http://www.genecards.org), we found that diseases associated with GRIK3, SULT4A1 and LRFN2 are schizophrenia, schizotypal personality disorder and neuronitis respectively, and SORBS1 is associated with insulin resistance. This evidence concerns the gene GRIK3 and Insulin resistance.