Previous studies have shown that Bcl-xL is critical for survival of platelets and potent Bcl-xL inhibitors such as ABT-737, ABT-263, WEHI-539, and BXI-72 exert their on-target toxicity on the platelets (thrombocytopenia) [14], [19], [31], [32]. This evidence concerns the gene BCL2L1 and Thrombocytopenia.