Consistent with this finding, Berg et al. demonstrated that IL-10-deficient murine models are prone to bacteria-induced carcinogenesis [95], whereas the adoptive transfer of IL-10-expressing CD4+CD25+ T cells into Rag2−/− (lymphocyte-deficient) mice inhibits colorectal inflammation and carcinomas [96, 97]. This evidence concerns the gene IL10 and carcinoma.