LDLR and coronary artery disorder: However, significant association was found between LDLR rs2228671 and CHD in European population (χ2 = 20.59, P < 0.0001 by genotype; χ2 = 20.26; OR = 1.180, 95% CI = 1.098–1.269, P < 0.0001 by allele; Table 3).