SDHD and hereditary pheochromocytoma-paraganglioma: In fact, Neumann et al. have shown that among 34 patients with mutations in SDHD gene, 79% had head and neck paraganglioma, 53% had pheochromocytoma, and 39% thoracic/abdominal paraganglioma, whereas 74% of the patients presented with multiple tumors [96].