IL10 and obesity due to melanocortin 4 receptor deficiency: In line with the aforementioned mechanism, along with the available agonists/analogues such as AM0010, SCH52000, RN1003, and IT9302, and its downstream signaling blockers such as CP-690 and CP-550, we hypothesized that IL-10 may have a protective role in lung injury, and more specifically, in acid aspiration induced lung injury in obesity.