BLNK and central nervous system cancer: The molecular mechanism of action of isoflavonoids is based on compound-specific inhibitory effects on protein tyrosine kinases, poly(ADP-ribose) polymerase cleavage, and caspase-3 activation in the case of GST 27,28, and inhibition of glioma-derived matrix metalloproteinases and phosphorylation of Akt and eIF4E in the case of BCA 29,30.