ESR1 and metastatic malignant neoplasm in the lymph nodes: A multivariable Cox regression model adjusted for tumor size, lymph node metastases, Grade, ER and PgR status, and KI67 labeling index (n = 79), confirmed that increased miR-10b RERs were associated with higher risk of disease progression (HR1.30; p < 0.001), distant metastases (HR1.34; p < 0.001) and worse overall survival (HR1.31; p = 0.003) (Table 2).