In addition, we illustrated the side effects of RYR by visualized and quantized indexes: ALT, AST (hepatic function), creatinine (renal function), CK (muscle effects), fasting blood glucose; the results showed that RYR has no significant increasing effect on serum CK level compared with placebo, which is preferable to statins because of the increasing statin-associated myalgias and CK increasing side effects[29]–[31]. This evidence concerns the gene GPT and Myalgia.