Furthermore, the expression pattern of CXCL16-CXCR6 was similar to that of CXCL12-CXCR4, the specific staining for both CXCR4 and CXCL12 could also be observed in three lung cancer cell lines despite of the difference of expression intensity in different cells. This evidence concerns the gene CXCR6 and lung carcinoma.