We performed stratified analysis between ≥65 and <65 years of age, and the association between T-LTPA and glycemic control and CVD risk factors did not differ in those of ≥65 and <65 years of age (interaction p for the age of 65 years and T-LTPA in the age- and sex-adjusted model was 0.167 for BMI, 0.947 for waist circumference, 0.070 for HbA1c, 0.420 for HOMA2-IR, 0.832 for triglyceride, 0.315 for HDL cholesterol and 0.704 for HS-CRP, respectively); (2) practising PA may have been restricted because of medical reasons, such as severe retinopathy or arthritis. The gene discussed is CRP; the disease is Arthritis.