As corresponding markers, we measured hemoglobin A1c (HbA1c), fasting plasma glucose, homeostasis model assessment 2 of insulin resistance (HOMA2-IR), low density lipoprotein (LDL) cholesterol, metabolic syndrome and its components, adiponectin and high sensitivity C-reactive protein (HS-CRP), which have been widely used in epidemiological studies [14]–[16]. The gene discussed is ADIPOQ; the disease is Insulin resistance.