CCL2 and myositis disease: In particular, chemokines, a class of small cytokines with potent chemotactic activity, such as IL-8 (CXCL8), Mig (CXCL9), IP-10 (CXCL10), RANTES (CCL5), and MCP-1 (CCL2), are overexpressed during myositis in infiltrating inflammatory cells, extracellular matrix, and muscle fibers [32, 44–47].