HBP1 and neoplasm: Our data showed that preserved HBP1 expression and lack of β-catenin nuclear accumulation had beneficial effects on prognosis (P = 0.039; hazard ratio [HR], 0.48; 95% confidence interval [CI], 0.24–0.96 for preserved HBP1 and P = 0.049; HR, 0.38; 95% CI, 0.24–0.99 for no β-catenin nuclear accumulation), even after adjusting for smoking habit, tumour type, tumour stage and lymph node status (P = 0.042 for preserved HBP1; P = 0.041 for no β-catenin nuclear accumulation; Table 1).