The results of TRf (t-test, t = -0.534, df = 63, p = 0.595) AAT (t-test, t = -1.531, df = 63, p = 0.131) HP (t-test, t = 0.105, df = 63, p = 0.917) and C3 (t-test, t = 0.031, df = 63, p = 0.976) for individual cases of perimenopausal women, with or without depression, are shown in Table 2, whereas the results for C4 (Mann–Whitney U, Z = -0.763, p = 0.445) and CRP (Mann–Whitney U, Z = -0.521, p = 0.603) are depicted in Table 3. This evidence concerns the gene CRP and major depressive disorder.