All six patients also had treatment for opportunistic infections such as TB or P. jiroveci pneumonia, but patient number 1 improved her symptoms, her lymphocytes count and CD4+ T cells count only when ganciclovir was given 17 days after she had finished trimethoprin sulfamethoxazole for P. jiroveci pneumonia with no improvement (Table 1 and Fig. 2: A and B) and patient number 2 had TB but the TB therapy was given only after his CD4+ lymphocytes had risen in response to anti-herpes virus treatment (Table 1 and Fig. 2: A and B). This evidence concerns the gene CD4 and tuberculosis.