CYP2E1 and Hepatic steatosis: The results showed that CYP2E1 suppression by CMZ completely blocked chronic ethanol-induced fatty liver in mice, which was illustrated by the decrease of the serum and hepatic TG levels and the pathological examination including H&E staining, the specific fat staining (Sudan III and oil red O staining), and the TEM examination (Table 2 and Fig. 1).