To add evidence for the direct interaction of miR-375 and YAP1 in CRC cells, we performed Ago2 immunoprecipitation (Ago2-IP) using lysates from miR-375 and Scr transfected HCT116 cells followed by YAP1 expression analysis of immunoprecipitated RNA. This evidence concerns the gene YAP1 and colorectal carcinoma.