Although there is little information about the causal genes in this region and little knowledge of how it modulates BP control., several genes near this region, including adducin (ADD2, 70 cM), G-protein–coupled receptor (GPR723, 68M), and transforming growth factor-α(TGFA, 70M), are associated with hypertension [31], [32]. Here, TGFA is linked to hypertensive disorder.