ACE and hypertensive disorder: During a parametric linkage analysis in 59 families from China with early onset hypertension, a link was detected to two chromosome regions that contained the LPL and dipeptidyl carboxipeptidase 1 (DCP1) genes; in the analysis, the greatest signal was for the region with the LPL gene46, which evidenced the association between dyslipidemia and hypertension, then this relationship was confirmed with a recent study associating 95 loci with high concentrations of lipids in plasma and among which the variants of the LPL and CEPT genes were identified.47